To Grace House from North of Lexington via southbound I-81/64: There are two options to Lexington from I-81S. 

Option 1: Take the first Lexington Exit (#195) onto US-11S. Follow US-11S, cross the Maury River, then bear right onto Business US-11S. Take Business US-11, S. Jefferson St., through downtown Lexington. Continue to follow the curve left from Jefferson St. onto White St., and make the immediate right turn onto S. Main St. Grace House will be on your left shortly after the light at Houston St. 

Option 2: Take the second Lexington Exit (#191) onto I-64W. Exit off of I-64W at exit #55. Turn left onto US-11S. Then follow the directions above.

To Grace House from South of Lexington via northbound I-81: Take exit #188B, US-60E toward Lexington. Continue on US-60E, crossing under US-11, into downtown Lexington. Turn left onto S. Jefferson St. Follow S. Jefferson St. to the curve left from Jefferson St. onto White St., and make the immediate right turn onto S. Main St. Grace House will be on your left shortly after the light at Houston St.